Refereed Journal Articles
Journal Covers:
2019
23. W.L. Lee, D. Wang, J. Wu, Q. Ge, H.Y. Low
Injection molding of superhydrophobic sub-micrometer surface topography on macroscopically curved objects: Experimental and simulation studies
ACS Applied Polymer Materials 1 (2019) 1547-1558. (Impact Factor, IF= 5) (Link)
22. J. Wu, W.L. Lee (co-first author), H.Y. Low
Nanostructured free‐form objects via a synergy of 3D printing and thermal nanoimprinting
Global Challenges 3 (2019) 1800083. (IF= 4.9) (Link)
2017
21. W.L. Lee, H.Y. Low, C. Ortiz
Geometry-dependent compressive responses in nanoimprinted submicron-structured shape memory polyurethane
Soft Matter 13 (2017) 3314-3327. (IF= 3.4) (Link)
20. S. Kharel, W.L. Lee, S.Y. Lee, S.C.J. Loo
Osmogen‐mediated one‐step technique of fabricating hollow microparticles for encapsulation and delivery of bioactive molecules
Macromolecular Bioscience 17 (2017) 1600328. (IF= 4.6) (Link)
2016
19. W.L. Lee, H.Y. Low
Geometry- and length scale-dependent deformation and recovery on micro- and nanopatterned shape memory polymer surfaces
Scientific Reports 6 (2016) 23686. (IF= 4.6) (Link)
2015
18. W.L. Lee, W.M. Guo, V.H.B. Ho, A. Saha, H.C. Chong, N.S. Tan, E.Y. Tan, S.C.J. Loo
Delivery of doxorubicin and paclitaxel from double-layered microparticles: The effects of layer thickness and dual-drug vs. single-drug loading
Acta Biomaterialia 27 (2015) 53-65. (IF= 9.7) (Link)
17. X. Wang, M.K. Sng, S. Foo, H.C. Chong, W.L. Lee, M.B.Y. Tang, K.W. Ng, B. Luo, C. Choong, M.T.C. Wong, B.M.K. Tong, S. Chiba, S.C.J. Loo, P. Zhu, N.S. Tan
Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment
Journal of Controlled Release 197 (2015) 138-147. (IF= 10.8) (Link)
2014
16. W.L. Lee, W.M. Guo, V.H.B. Ho, A. Saha, H.C. Chong, N.S. Tan, E. Widjaja, E.Y. Tan, S.C.J. Loo
Inhibition of 3-D tumor spheroids by timed-released hydrophilic and hydrophobic drugs from multilayered polymeric microparticles
Small 10 (2014) 3986-3996. (IF=13.3) (Link)
15. W.L. Lee, J.W.M. Tan (co-first author), C.N. Tan, S.C.J. Loo
Modulating drug release from gastric-floating microcapsules through spray-coating layers
PLoS One 9 (2014) e114284. (IF= 3.7) (Link)
14. C.L. Huang, W.L. Lee, S.C.J. Loo
Drug-eluting scaffolds for bone and cartilage regeneration
Drug Discovery Today 19 (2014) 714-724. (Featured as the cover story) (IF= 7.4) (Link)
2013
13. W.L. Lee, P. Wee (co-first author), C. Nugraha, S.C.J. Loo
Gastric-floating microcapsules provide controlled and sustained release of multiple cardiovascular drugs
Journal of Materials Chemistry B 1 (2013) 1090-1095. (IF= 7) (Link)
12. M.P. Lim, W.L. Lee, E. Widjaja, S.C.J. Loo
One-step fabrication of core-shell structured alginate-PLGA/PLLA microparticles as a novel drug delivery system for water soluble drugs
Biomaterials Science 1 (2013) 486-493. (IF= 6.6) (Link)
2012
11. W.L. Lee, P. Yu, M. Hong, E. Widjaja, S.C.J. Loo
Designing multilayered particulate systems for tunable drug release profiles
Acta Biomaterialia 8 (2012) 2271-2278. (IF= 9.7) (Link)
10. Y.L. Khung, W.L. Lee (co-first author), K.L. Chui, Y. Liu, M.P. Lim, C.L. Huang, S.C.J. Loo
Microencapsulation of dye- and drug-loaded particles for imaging and controlled release of multiple drugs
Advanced Healthcare Materials 1 (2012) 159-163. (IF= 10) (Link)
9. W.L. Lee, S.C.J. Loo
Revolutionizing drug delivery through biodegradable multilayered particles
Journal of Drug Targeting 20 (2012) 633-647. (Invited review article) (IF= 4.5) (Link)
8. W.L. Lee, W.X. Shi, Z.Y. Low, S. Li, S.C.J. Loo
Modeling of drug release from biodegradable triple-layered microparticles
Journal of Biomedical Materials Research: Part A 100A (2012) 3353-3362. (IF= 4.9) (Link)
7. W.L. Lee, Y.C. Seh, E. Widjaja, H.C. Chong, N.S. Tan, S.C.J. Loo
Fabrication and drug release study of double-layered microparticles of various sizes
Journal of Pharmaceutical Sciences 101 (2012) 2787-2797. (IF= 3.8) (Link)
6. W.L. Lee, E. Widjaja, S.C.J. Loo
Designing drug-loaded multi-layered polymeric microparticles
Journal of Material Science: Materials in Medicine 23 (2012) 81-88. (Selected Papers from the 24th European Conference on Biomaterials, Dublin, Ireland, September 2011) (IF= 3.7) (Link)
2011
5. W.L. Lee, C. Loei, E. Widjaja, S.C.J. Loo
Altering the drug release profiles of double-layered ternary-phase microparticles
Journal of Controlled Release 151 (2011) 229-238. (IF= 10.8) (Link)
2010
4. W.L. Lee, E. Widjaja, S.C.J. Loo
One-step fabrication of triple-layered polymeric microparticles with layer localization of drugs as a novel drug-delivery system
Small 6 (2010) 1003-1011. (IF= 13.3) (Link)
3. W.L. Lee, W.L. Foo, E. Widjaja, S.C.J. Loo
Manipulation of process parameters to achieve different ternary-phase microparticle configurations
Acta Biomaterialia 6 (2010) 1342-1352. (IF= 9.7) (Link)
2. W.L. Lee, M. Hong, E. Widjaja, S.C.J. Loo
Formation and degradation of biodegradable triple-layered microparticles
Macromolecular Rapid Communications 31 (2010) 1193-1200. (IF= 4.6) (Link)
1. E. Widjaja, W.L. Lee, S.C.J. Loo
Application of Raman microscopy to biodegradable double-walled microspheres
Analytical Chemistry 82 (2010) 1277-1282. (Featured as the cover page and Research Profile, and highlighted under the journal's News section.) (IF= 7.4) (Link)
Patents
5. S.C.J. Loo, S. Kharel, W.L. Lee
Method of preparing hollow microparticles and hollow microparticles prepared thereof
(WO/2016/089309) PCT/SG2015/050483 filed on 2 Dec 2015. (Link)
4. S.C.J. Loo, W.L. Lee, P. Wee
Floating capsules encapsulating particles loaded with one or more drugs
(WO/2014/027956) PCT/SG2013/000282 filed on 8 Jul 2013, and granted (US Patent No. 9,381,163) on 5 Jul 2016, and granted (SG Patent No. 11201500227S) on 29 Nov 2016. (Link)
3. S.C.J. Loo, M.P. Lim, W.L. Lee
Methods of manufacturing core-shell microparticles and microparticles formed thereof
(WO/2013/119183) PCT/SG2013/000051 filed on 6 Feb 2013, and granted (SG Patent No. 11201404038P) on 2 Mar 2015. (Link)
2. S.C.J. Loo, Y.L. Khung, W.L. Lee
Method for encapsulating particles
(WO/2012/071013) PCT/SG2011/000413 filed on 24 Nov 2011, and granted (SG Patent No. 190009) on 24 Apr 2014, and granted (EP Patent No. 2642984) on 11 Jan 2017, and granted (US Patent No. 9,616,031) on 11 Apr 2017. (Link)
1. S.C.J. Loo, W.L. Lee
Multi-phase microparticles and method of manufacturing multi-phase microparticles
(WO/2010/140987) PCT/SG2010/000215 filed on 7 Jun 2010, and granted (SG Patent No. 176239) on 14 Dec 2012, and granted (CN Patent No. ZL 2010 8 0034273.8) on 23 Nov 2016, and granted (EP Patent No. 2437879) on 26 Jul 2017. (Link)
Conference Abstracts and Proceedings
4. W.L. Lee, H.Y. Low, C. Ortiz
Mechanically deformable and programmable nanoscale surface textures with tunable wetting and mechanical properties
Journal of Material Sciences and Engineering 5 (7 Suppl) (2016) 99.
3. X. Wang, S. Foo, H. Chong, W.L. Lee, M. Tang, S. Chiba, K.W. Ng, S.C.J. Loo, N.S. Tan
Topical controlled release of PPAR beta/delta agonist from microparticles accelerates diabetic wound healing
Journal of Investigative Dermatology 133 (2013) S251. (IF= 6.5)
2. S.C.J. Loo, W.L. Lee, E. Widjaja
Designing multi-layered polymeric microparticles for delivery of multiple drug entities
CHEMECA 2011: Engineering a Better World (2011) 88.
1. W.L. Lee, E. Widjaja, S.C.J. Loo
Designing multi-layered polymeric microparticles for drug delivery
Singapore Medical Journal 52(1 Suppl) (2011) S59. (IF= 2.7)