top of page

Refereed Journal Articles

Refereed Journal Articles

Journal Covers:

2019

23. W.L. Lee, D. Wang, J. Wu, Q. Ge, H.Y. Low

Injection molding of superhydrophobic sub-micrometer surface topography on macroscopically curved objects: Experimental and simulation studies

ACS Applied Polymer Materials 1 (2019) 1547-1558. (Impact Factor, IF= 5) (Link)

22. J. Wu, W.L. Lee (co-first author), H.Y. Low

Nanostructured free‐form objects via a synergy of 3D printing and thermal nanoimprinting

Global Challenges 3 (2019) 1800083. (IF= 4.9) (Link)

 

 

2017

21. W.L. Lee, H.Y. Low, C. Ortiz

Geometry-dependent compressive responses in nanoimprinted submicron-structured shape memory polyurethane

Soft Matter 13 (2017) 3314-3327. (IF= 3.4) (Link)

20. S. Kharel, W.L. Lee, S.Y. Lee, S.C.J. Loo

Osmogen‐mediated one‐step technique of fabricating hollow microparticles for encapsulation and delivery of bioactive molecules

Macromolecular Bioscience 17 (2017) 1600328. (IF= 4.6) (Link)

2016

 

19. W.L. Lee, H.Y. Low

Geometry- and length scale-dependent deformation and recovery on micro- and nanopatterned shape memory polymer surfaces

Scientific Reports 6 (2016) 23686. (IF= 4.6) (Link)

2015

 

18. W.L. Lee,  W.M. Guo, V.H.B. Ho, A. Saha, H.C. Chong, N.S. Tan, E.Y. Tan, S.C.J. Loo

Delivery of doxorubicin and paclitaxel from double-layered microparticles: The effects of layer thickness and dual-drug vs. single-drug loading

Acta Biomaterialia 27 (2015) 53-65. (IF= 9.7) (Link)

 

17. X. Wang, M.K. Sng, S. Foo, H.C. Chong, W.L. Lee, M.B.Y. Tang, K.W. Ng, B. Luo, C. Choong, M.T.C. Wong, B.M.K. Tong, S. Chiba, S.C.J. Loo, P. Zhu, N.S. Tan

Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment

Journal of Controlled Release 197 (2015) 138-147. (IF= 10.8) (Link)

 

2014

 

16. W.L. Lee,  W.M. Guo, V.H.B. Ho, A. Saha, H.C. Chong, N.S. Tan, E. Widjaja, E.Y. Tan, S.C.J. Loo

Inhibition of 3-D tumor spheroids by timed-released hydrophilic and hydrophobic drugs from multilayered polymeric microparticles

Small 10 (2014) 3986-3996. (IF=13.3) (Link)

 

15. W.L. Lee, J.W.M. Tan (co-first author), C.N. Tan, S.C.J. Loo

Modulating drug release from gastric-floating microcapsules through spray-coating layers

PLoS One 9 (2014) e114284. (IF= 3.7) (Link)

 

14. C.L. Huang, W.L. Lee, S.C.J. Loo

Drug-eluting scaffolds for bone and cartilage regeneration

Drug Discovery Today 19 (2014) 714-724. (Featured as the cover story) (IF= 7.4) (Link)

 

2013

 

13. W.L. Lee, P. Wee (co-first author), C. Nugraha, S.C.J. Loo

Gastric-floating microcapsules provide controlled and sustained release of multiple cardiovascular drugs

Journal of Materials Chemistry B 1 (2013) 1090-1095. (IF= 7) (Link)

 

12. M.P. Lim, W.L. Lee, E. Widjaja, S.C.J. Loo

One-step fabrication of core-shell structured alginate-PLGA/PLLA microparticles as a novel drug delivery system for water soluble drugs

Biomaterials Science 1 (2013) 486-493. (IF= 6.6) (Link)

 

2012

 

11. W.L. Lee, P. Yu, M. Hong, E. Widjaja, S.C.J. Loo

Designing multilayered particulate systems for tunable drug release profiles

Acta Biomaterialia 8 (2012) 2271-2278. (IF= 9.7) (Link)

 

10. Y.L. Khung, W.L. Lee (co-first author), K.L. Chui, Y. Liu, M.P. Lim, C.L. Huang, S.C.J. Loo

Microencapsulation of dye- and drug-loaded particles for imaging and controlled release of multiple drugs

Advanced Healthcare Materials 1 (2012) 159-163. (IF= 10) (Link)

 

9. W.L. Lee, S.C.J. Loo

Revolutionizing drug delivery through biodegradable multilayered particles

Journal of Drug Targeting 20 (2012) 633-647. (Invited review article) (IF= 4.5) (Link)

 

8. W.L. Lee, W.X. Shi, Z.Y. Low, S. Li, S.C.J. Loo

Modeling of drug release from biodegradable triple-layered microparticles

Journal of Biomedical Materials Research: Part A 100A (2012) 3353-3362. (IF=  4.9) (Link)

 

7. W.L. Lee, Y.C. Seh, E. Widjaja, H.C. Chong, N.S. Tan, S.C.J. Loo

Fabrication and drug release study of double-layered microparticles of various sizes

Journal of Pharmaceutical Sciences 101 (2012) 2787-2797. (IF= 3.8) (Link)

 

6. W.L. Lee, E. Widjaja, S.C.J. Loo

Designing drug-loaded multi-layered polymeric microparticles

Journal of Material Science: Materials in Medicine 23 (2012) 81-88. (Selected Papers from the 24th European Conference on Biomaterials, Dublin, Ireland, September 2011) (IF= 3.7) (Link)

 

2011

 

5. W.L. Lee, C. Loei, E. Widjaja, S.C.J. Loo

Altering the drug release profiles of double-layered ternary-phase microparticles

Journal of Controlled Release 151 (2011) 229-238. (IF= 10.8) (Link)

 

2010

 

4. W.L. Lee, E. Widjaja, S.C.J. Loo

One-step fabrication of triple-layered polymeric microparticles with layer localization of drugs as a novel drug-delivery system

Small 6 (2010) 1003-1011. (IF= 13.3) (Link)

 

3. W.L. Lee, W.L. Foo, E. Widjaja, S.C.J. Loo

Manipulation of process parameters to achieve different ternary-phase microparticle configurations

Acta Biomaterialia 6 (2010) 1342-1352. (IF= 9.7) (Link)

 

2. W.L. Lee, M. Hong, E. Widjaja, S.C.J. Loo

Formation and degradation of biodegradable triple-layered microparticles

Macromolecular Rapid Communications 31 (2010) 1193-1200. (IF= 4.6) (Link)

 

1. E. Widjaja, W.L. Lee, S.C.J. Loo

Application of Raman microscopy to biodegradable double-walled microspheres

Analytical Chemistry 82 (2010) 1277-1282. (Featured as the cover page and Research Profile, and highlighted under the journal's News section.) (IF= 7.4) (Link)

Patents

5. S.C.J. Loo, S. Kharel, W.L. Lee

Method of preparing hollow microparticles and hollow microparticles prepared thereof

(WO/2016/089309) PCT/SG2015/050483 filed on 2 Dec 2015. (Link)

 

4. S.C.J. Loo, W.L. Lee, P. Wee

Floating capsules encapsulating particles loaded with one or more drugs

(WO/2014/027956) PCT/SG2013/000282 filed on 8 Jul 2013, and granted (US Patent No. 9,381,163) on 5 Jul 2016, and granted (SG Patent No. 11201500227S) on 29 Nov 2016. (Link)

 

3. S.C.J. Loo, M.P. Lim, W.L. Lee

Methods of manufacturing core-shell microparticles and microparticles formed thereof

(WO/2013/119183) PCT/SG2013/000051 filed on 6 Feb 2013, and granted (SG Patent No. 11201404038P) on 2 Mar 2015. (Link)

 

2. S.C.J. Loo, Y.L. Khung, W.L. Lee

Method for encapsulating particles

(WO/2012/071013) PCT/SG2011/000413 filed on 24 Nov 2011, and granted (SG Patent No. 190009) on 24 Apr 2014, and granted (EP Patent No. 2642984) on 11 Jan 2017, and granted (US Patent No. 9,616,031) on 11 Apr 2017. (Link)

 

1. S.C.J. Loo, W.L. Lee

Multi-phase microparticles and method of manufacturing multi-phase microparticles

(WO/2010/140987) PCT/SG2010/000215 filed on 7 Jun 2010, and granted (SG Patent No. 176239) on 14 Dec 2012, and granted (CN Patent No. ZL 2010 8 0034273.8) on 23 Nov 2016, and granted (EP Patent No. 2437879) on 26 Jul 2017. (Link)

Patents

Conference Abstracts and Proceedings

Conference Abstracts and Proceedings

4. W.L. Lee, H.Y. Low, C. Ortiz

Mechanically deformable and programmable nanoscale surface textures with tunable wetting and mechanical properties

Journal of Material Sciences and Engineering 5 (7 Suppl) (2016) 99.

 

3. X. Wang, S. Foo, H. Chong, W.L. Lee, M. Tang, S. Chiba, K.W. Ng, S.C.J. Loo, N.S. Tan

Topical controlled release of PPAR beta/delta agonist from microparticles accelerates diabetic wound healing

Journal of Investigative Dermatology 133 (2013) S251. (IF= 6.5)

2. S.C.J. Loo, W.L. Lee, E. Widjaja

Designing multi-layered polymeric microparticles for delivery of multiple drug entities

CHEMECA 2011: Engineering a Better World (2011) 88.

 

1. W.L. Lee, E. Widjaja, S.C.J. Loo

Designing multi-layered polymeric microparticles for drug delivery

Singapore Medical Journal 52(1 Suppl) (2011) S59. (IF= 2.7)

bottom of page